Friday, February 27, 2015

Cure Alzheimer's Driving Genes to Therapies

"Our ultimate goal is to develop effective drug therapies at three different points in the pathological cascade of the disease to prevent, inhibit and cure Alzheimer’s."

Building on its enormously successful “Whole Genome Sequencing” Project, which identified nearly 1,000 new genetic mutations in more than 50 different genes, Cure Alzheimer's Fund has announced a new, even more ambitious multi year, $50 million plus program titled “Genes to Therapies” (G2T).

Cure Alzheimer's Driving Genes to Therapies

The mission of the Cure Alzheimer's Fund is to fund research with the highest probability of preventing, slowing, or reversing Alzheimer’s disease through venture-based philanthropy.

Alzheimer's Reading Room

Thursday, February 26, 2015

Always Be Kinder Than You Feel

Let's face it, Alzheimer's patients often say things that seem nonsensical to us; or, say things that leave us exasperated, confused, frustrated, and sometimes angry.

It is not easy to listen and understand.

Always Be Kinder Than You Feel

What does this mean to you?

Wednesday, February 25, 2015

The Woman Who Wouldn't Sit Down to Pee

Our reader Nita asked in an email.
My sister has Alzheimer's. She is almost 64 and in stage 6. Incontinence.

My problem, when I visit her at the memory care center is trying to get her to sit down when I take her to pee.

I get her pants and pull-up down and ask her to sit. She smiles and says OK, OK, OK, and keeps smiling but doesn't sit.

I like to make sure she "goes" before I take her out to lunch but getting her to sit is an increasing problem. Any good ideas are welcome. Thanks, Nita

Tuesday, February 24, 2015

Simple Skin Test May Detect Alzheimer's

Until now, pathological confirmation of Alzheimer's was not possible without a brain biopsy, so the disease often goes unrecognized, or patients are misdiagnosed.

Alzheimer's Reading Room

Simple Skin Test May Detect Alzheimer's | Alzheimer's Reding Room

There can be no doubt that a simple test that could accurately diagnose Alzheimer's disease would make an important difference. It would answer this simple question - Is it Alzheimer's or something else?

A large fraction of Alzheimer's patients are misdiagnosed; and, in some cases they are suffering from something that can be treated. Imagine the angst and fear that some families face unnecessarily.

The study showed that skin biopsies can be used to detect elevated levels of abnormal proteins.
"Until now, pathological confirmation was not possible without a brain biopsy, so these diseases often go unrecognized until after the disease has progressed," said study author Ildefonso Rodriguez-Leyva, MD, at Central Hospital at the University of San Luis Potosi in San Luis Potosi, Mexico. 
"We hypothesized that since skin has the same origin as brain tissue while in the embryo that they might also show the same abnormal proteins. This new test offers a potential biomarker that may allow doctors to identify and diagnose these diseases earlier on."