Monday, March 31, 2008

Lilly Launches Its First Phase III Trial for Treatment of Alzheimer's Disease


clipped from www.prnewswire.com
Late-stage IDENTITY study of once-daily, oral agent is now enrolling
patients
Eli Lilly and Company
(NYSE: LLY) has announced today the start of a Phase III clinical trial
studying LY450139, an investigational gamma secretase inhibitor for the
treatment of mild to moderate Alzheimer's disease.
Slowing the rate of disease progression could preserve independent
functioning and quality of life for Alzheimer's patients in the milder
stages of the disease, potentially delaying the onset of the severe stages
of the disease.
LY450139 is being tested
to see if it can slow the progression associated with Alzheimer's disease
by inhibiting gamma-secretase, an enzyme that can create a sticky protein
called amyloid beta.
IDENTITY is a randomized, double-blind, placebo-controlled trial that
will be conducted in the U.S. and 21 additional countries.
information regarding the IDENTITY trial, including global
recruitment sites, may be found at clinicaltrials.gov

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Bob DeMarco is a citizen journalist, blogger, and Caregiver. In addition to being an experienced writer he taught at the University of Georgia , was an Associate Director and Limited Partner at Bear Stearns, the CEO of IP Group, and is a mentor. Bob currently resides in Delray Beach, FL where he cares for his mother, Dorothy, who suffers from Alzheimer's disease. He has written more than 500 articles with more than 11,000 links to his work on the Internet. His content has been syndicated on Reuters, the Wall Street Journal, Fox News, Pluck, Blog Critics, and a growing list of newspaper websites. Bob is actively seeking syndication and writing assignments.