The Alzheimer's Reading Room Knowledge Base contains more than 4,901 articles. These articles were written to answer and address the most difficult problems and issues faced in Alzheimer's and dementia care. At its core the ARR is about helping everyone to better understand, cope, and communicate with a person living with dementia.
The researchers discovered the medicine, CNI-14493, can transform amyloid into a form that doesn't aggregate to form plaques in the brain and also neutralizes the toxicity of the amyloid.
In his latest work, al-Abed was looking for a way to target the amyloid plaques that clump together between neurons in the brains of people with Alzheimer's disease.
Al-Abed, along with Michael Bacher and Richard Dodel of Marburg University in Germany, found the amyloid burden in the brain was reduced by 70 percent to 85 percent in areas hard hit in Alzheimer's patients -- the cortex and the hippocampus.