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Monday, March 16, 2009

A Simple Balance Test May Detect Alzheimer's Early


A Simple Balance Test May Detect Alzheimer's EarlyThe announcement of this article caught my attention. I have written several times about the very distinctive sound my mother's feet started making well before she was diagnosed with Alzheimer's dementia. The sound is difficult to describe, but I first heard it when she started scuffing her shoes on the ground as she walked. The sound was unique and it actually disconcerted me. When I mentioned this to my family and friends they all said the same thing, "she is getting old". I dismissed it for a long time, but looking back I now know it was a sign of mild cognitive impairment--often an early stage of dementia.

This new research about a simple balance test and the ability of this test to detect mild cognitive impairment is important. I suggest you try this one leg balance test. Then, if you have an elderly parent or grandparent you might have them try it from time to time.


This blog is loaded with articles about the importance of detecting Alzheimer's and dementia early. The benefits of an early diagnosis are many, and are not limited to the positive outcome of getting the correct medications early on.

A simple balance test may predict cognitive decline in Alzheimer's Disease, according to a study published in the March 2009 issue of the Journal of Alzheimer's Disease.

This study was carried out in 16 university hospital departments of neurology, geriatrics or psychiatry in ten cities with 686 outpatients suffering from AD. This population is representative of the AD population seen by clinicians in daily practice. Patients were evaluated by a geriatrician every six months for up to two years, and their degree of cognitive impairment was measured using the Mini Mental State Examination (MMSE). At the same time, a "one-leg balance" (OLB) test was given, where a participant was asked to stand on one leg for as long as possible. The OLB test was reported as abnormal when the participant was unable to stand on one leg for 5 seconds or more.

Participants with an abnormal OLB at baseline or/and during the follow-up showed significantly more cognitive decline at 12, 18 and 24 months than the participants with a OLB test normal at baseline and normal during the follow-up. The worst condition (having an abnormal OLB at baseline and during the follow-up= no improvement) was associated with a mean adjusted cognitive decline of 9.2 points. The best condition (having a normal OLB at baseline and during the follow-up = no worsening) was associated with a mean adjusted cognitive decline of 3.8 points.

Senior Investigator Yves Rolland, Inserm and the University of Toulouse, France, states, "Our results suggested that an abnormal OLB is a marker of more advanced dementia (worst baseline characteristic) and an independent predictor of cognitive decline in AD. Our results reinforce in an AD population, the growing evidence suggesting a link between physical performances and cognitive decline. If these results are confirmed by other data, the OLB test could be adopted in clinical practice to identify AD patients at high risk of rapid cognitive decline."

The article is "An Abnormal 'One-leg Balance' Test Predicts Cognitive Decline During Alzheimer's Disease" by Yves Rolland, Gabor Abellan van Kan, Fati Nourhashemi, Sandrine Andrieu, Christelle Cantet, Sophie Guyonnet-Gillette and Bruno Vellas It is published in the Journal of Alzheimer's Disease 16:3 (March 2009).


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Bob DeMarco
Bob DeMarco is the Founder of the Alzheimer's Reading Room (ARR). Bob is a recognized Influencer, speaker, and expert in the Alzheimer's and Dementia Community Worldwide. The Alzheimer's Reading Knowledge Base contains more than 4,000 articles, and the ARR has more than 343,000 links on the Internet. Bob lives in Delray Beach, FL.
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